News for Healthier Living
Genetic Testing Reduces Risks From Chemotherapy for Gastrointestinal Cancer Patients
For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact how their bodies process the drugs used to treat their disease. Testing for variants in two genes before starting chemotherapy can significantly improve patient safety by providing physicians with information to help tailor doses, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Those who were found to have one of the genes had half as many side effects in half, as compared to patients with the genes that were given standard doses without testing, according to results published today in JCO Precision Oncology.
August 7, 2025
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