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Cancer Drug Eliminates Aggressive Cancers in Clinical Trial

Rockefeller scientists engineered an enhanced CD40 agonist antibody to fight cancer that has improved efficacy and is administered in a way that limits serious side effects. In recent clinical trial of 12 patients, six patients saw their tumors shrink, including two who experienced complete remission. The findings have sparked a number of other clinical trials involving a variety of cancers.

August 14, 2025


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