News for Healthier Living
Off-Label, on Target: New Hope for Children with Inflammatory Bowel Disease
Off-label treatments are offering new hope to children battling inflammatory bowel disease (IBD), especially when conventional therapies fall short. A comprehensive new review explores the real-world application of biologics and small molecule drugs originally approved for adults--such as ustekinumab, vedolizumab, upadacitinib, and ozanimod--in pediatric IBD cases. These alternative approaches are showing encouraging results, including higher rates of steroid-free clinical remission and improved disease management in treatment-resistant patients. While these therapies remain technically unapproved for pediatric use, growing evidence suggests they may provide critical relief when other options have been exhausted. The review underscores both the promise and the caution needed when venturing into off-label territory.
August 11, 2025
August 14 2025August 13 2025August 12 2025August 11 2025August 10 2025August 9 2025August 8 2025August 7 2025August 6 2025August 5 2025August 4 2025August 3 2025August 2 2025August 1 2025 - Co-Sleeping Can Do More Harm Than Good
- The Brain Can Be Targeted to Treat Type 1 Diabetes
- Mayo Clinic Researchers Find "Sugar Coating" Cells Can Protect Those Typically Destroyed in Type 1 Diabetes
- "And" vs. "Then": What Words in Online Reviews Tell US About Hospital Visits
- Fear of Hair Loss May Keep Cancer Patients from Starting Treatment, Study Finds
- Research Tip Sheet: Heart Attack, Muscular Dystrophy, Neuroprosthetics
- Medicare Could Save $3.6B Without Risk to Older Adults, Study Suggests
- New Health Record System Aims to Make Sharing Info Easier, Trump Says
- Searching for a Lethal Needle in a Haystack: Traces of Highly Potent Synthetic Opioids Found in Used Syringes
- Hulk Hogan’s Cause of Death Revealed: Heart Attack at Age 71
- Justin Timberlake Reveals Lyme Disease Struggle After Tour
- How the COVID-19 Pandemic Affected Parents and Youth: Thorns and Silver Linings
- Moffitt Cancer Center Launches Study to Improve Advanced Lung Cancer Outcomes in the Black Community
- Heart Activity Reveals Early Signs of Problem Alcohol Use
- Among Aging Adults--Especially Women--Problematic Alcohol Use Has Become More Common
- Brief, Low-Cost Education May Discourage Alcohol Use during Pregnancy
- Women's Hormonal Stress System Is Less Reactive to High-Dose Alcohol, Potentially Contributing to Tolerance and Raising the Risk of Alcohol Use Disorder
- Death, Grief, and Cicadas: How a Mother is Helping Others Navigate Loss
- Hearing Loss Can Keep Young People From Education, Jobs
- Are Some 'Low-Grade' Prostate Cancers More Deadly Than Thought?
- Heavy Weed Use Brings High Risk for Oral Cancers
- Coming Soon: An At-Home Patch to Spot Skin Cancers?
- Deaths to Youths Inhaling 'Laughing Gas' Are Soaring
- International Respiratory experts Use World Lung Cancer Day to Stress the Importance of Screening, Risk Factor Awareness
- When Local Homicide Rates Rise, Suicides Rise Soon After
- A Surgical Robot with Eyes of Its Own
- Bioactive Dressings: A Promising Approach for Diabetic Wound Management
- Mayo Clinic Treats First Person in the US with a Novel Radiopharmaceutical Therapy for Breast Cancer
- New Insights: How Gut Microbiota and Isoflavones May Alleviate Geniposide Hepatotoxicity
- PICU-specific Strategies Address Gaps in CAUTI Prevention
- August 2025 Issue of Neurosurgical Focus: "Surgical Management of Diffusely Infiltrative Gliomas"
|
|
|
|
|